Simon J R Heales Selected Research

Simon J R Heales Research Topics

Disease

7	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 02/2003
7	Mitochondrial Diseases (Mitochondrial Disease) 01/2016 - 02/2002
5	Epilepsy (Aura) 01/2018 - 04/2005
3	Drug Resistant Epilepsy 12/2023 - 01/2018
3	Seizures (Absence Seizure) 12/2023 - 04/2005
3	Nervous System Diseases (Neurological Disorders) 01/2021 - 02/2005
3	Parkinsonian Disorders (Parkinsonism) 01/2021 - 07/2014
3	Barth Syndrome 01/2016 - 09/2013
3	Astrocytoma (Pilocytic Astrocytoma) 04/2013 - 07/2008
2	Inflammation (Inflammations) 01/2021 - 12/2002
2	Aromatic amino acid decarboxylase deficiency 01/2021 - 07/2010
2	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 04/2007
2	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 07/2014 - 06/2009
2	Beta-Hydroxyisobutyryl CoA Deacylase Deficiency 12/2013 - 01/2007
2	Neuroblastoma 04/2013 - 07/2010
2	Parkinson Disease (Parkinson's Disease) 09/2012 - 04/2011
2	Movement Disorders (Movement Disorder) 06/2009 - 05/2009
2	Myotoxicity 01/2009 - 01/2005
1	Cerebral Palsy (Spastic Diplegia) 12/2023
1	Heart Arrest (Cardiac Arrest) 12/2023
1	Hypokinesia (Bradykinesia) 01/2021
1	Hyperkinesis 01/2021
1	Tremor (Tremors) 01/2021
1	Ketosis 01/2021
1	Dystonia (Limb Dystonia) 01/2020
1	Fabry Disease (Fabry's Disease) 09/2019
1	Optic Atrophy 01/2019
1	Polyneuropathies (Polyneuropathy) 01/2019
1	Neoplasms (Cancer) 01/2018
1	Type 2 Diabetes Mellitus (MODY) 01/2018
1	Insulin Resistance 01/2018
1	Pyridoxamine 5-Prime-Phosphate Oxidase Deficiency 01/2017
1	Leigh Disease (Leigh's Disease) 01/2016
1	Weight Loss (Weight Reduction) 01/2016
1	VLCAD deficiency 01/2016
1	Metabolic Diseases (Metabolic Disease) 01/2016
1	Pyruvate Dehydrogenase Complex Deficiency Disease 12/2013
1	Multiple Mitochondrial Dysfunctions Syndrome 12/2013
1	Dopa-responsive Dystonia 04/2011
1	Vitamin B 6 Deficiency (Pyridoxine Deficiency) 07/2010
1	Infantile Parkinsonism-Dystonia 06/2009
1	Muscular Diseases (Myopathy) 01/2009
1	Inborn Errors Metabolism (Inborn Errors of Metabolism) 04/2007
1	Ataxia (Dyssynergia) 04/2007
1	Hypoxia (Hypoxemia) 04/2006
1	Brain Diseases (Brain Disorder) 04/2005

Drug/Important Bio-Agent (IBA)

6	Dopamine (Intropin)FDA LinkGeneric 01/2021 - 04/2007
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2006
4	Cardiolipins (Cardiolipin)IBA 01/2016 - 07/2008
4	UbiquinoneIBA 05/2013 - 04/2007
3	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2021 - 06/2009
3	Neurotransmitter Agents (Neurotransmitter)IBA 01/2020 - 04/2005
3	PyridoxalIBA 01/2019 - 04/2005
3	coenzyme Q10 (CoQ10)IBA 05/2013 - 04/2007
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2007 - 02/2003
2	decanoic acid (capric acid)IBA 01/2021 - 01/2016
2	Aromatic-L-Amino-Acid DecarboxylasesIBA 01/2021 - 07/2010
2	Serotonin (5 Hydroxytryptamine)IBA 01/2021 - 04/2007
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 01/2016
2	Oxidoreductases (Dehydrogenase)IBA 01/2017 - 04/2005
2	EnzymesIBA 01/2017 - 01/2016
2	Valine (L-Valine)FDA Link 12/2013 - 01/2007
2	Glutathione (Reduced Glutathione)IBA 04/2011 - 02/2002
2	Peroxynitrous Acid (Peroxynitrite)IBA 01/2010 - 07/2008
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2009 - 01/2005
1	insulin receptor-related receptor (IRR)IBA 12/2023
1	Triglycerides (Triacylglycerol)IBA 01/2021
1	SugarsIBA 01/2021
1	5'- O- (4,4'- dimethoxytrityl)thymidine- 3'- O- (2,4- dinitrophenyl) succinate (DTDS)IBA 01/2021
1	octanoic acid (caprylic acid)IBA 01/2021
1	ClathrinIBA 01/2020
1	Homovanillic AcidIBA 01/2020
1	AuxilinsIBA 01/2020
1	GalactosidasesIBA 09/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	Thioctic Acid (Lipoic Acid)IBA 12/2013
1	IronIBA 12/2013
1	Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA 12/2013
1	5-methyltetrahydrofolateIBA 12/2013
1	Glucosylceramidase (Glucocerebrosidase)IBA 09/2012
1	Guanosine Triphosphate (GTP)IBA 04/2011
1	AntioxidantsIBA 04/2011
1	BezafibrateIBA 11/2010
1	Levodopa (L Dopa)FDA LinkGeneric 07/2010
1	Itraconazole (Sporanox)FDA LinkGeneric 01/2009
1	Simvastatin (Zocor)FDA LinkGeneric 01/2009
1	Coenzyme A (CoA)IBA 01/2009
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2009
1	Conditioned Culture MediaIBA 07/2008
1	Oxidants (Oxidizing Agents)IBA 07/2008
1	CopperIBA 07/2008
1	sapropterin (tetrahydrobiopterin)FDA Link 04/2007
1	acylcarnitineIBA 01/2007
1	Pyridoxal Phosphate (Pyridoxal 5 Phosphate)IBA 04/2005
1	Pyridoxine (Pyridoxin)FDA LinkGeneric 04/2005

Therapy/Procedure

5	Ketogenic Diet 12/2023 - 05/2014
4	Therapeutics 01/2021 - 01/2017
1	Palliative Care (Palliative Therapy) 01/2021
1	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 01/2018
1	Drug Therapy (Chemotherapy) 01/2016